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Choosing between the AirSense 10 and the AirSense 11 from ResMed? This is one of the most common questions in the world of CPAP. Both devices share many core features - the AutoSet algorithm, integrated humidification, pressure ramp, EPR. The real question is: do you need the improvements of the 11th generation, or does the AirSense 10 still meet your needs?
This guide covers the concrete differences: connectivity, algorithm, humidifier, accessories, the myAir app and a recommendation based on your profile.
- 30-second summary
- Full comparison table
- Key differences
- Accessory compatibility
- myAir: what experience on each device?
- Which device is right for you?
30-second summary
AirSense 10 AutoSet
DiscontinuedReleased in 2014. Dial control + LCD screen. Hugely popular, appreciated for its simplicity and reliability. No longer manufactured - limited stock.
AirSense 11 AutoSet
Current modelReleased in 2021. Touchscreen, native cellular connectivity, improved algorithm, enhanced myAir (Care Check-In, Personal Therapy Assistant). OTA updates. HumidAir 11 Cleanable humidifier.
Full comparison table: AirSense 10 vs AirSense 11
| Feature | AirSense 10 AutoSet | AirSense 11 AutoSet |
|---|---|---|
| Status | Discontinued (end of production) | Current model |
| Interface | Rotary dial + colour LCD screen | Colour touchscreen |
| Connectivity | WiFi module (depending on version) | Native integrated cellular (no WiFi required) |
| AutoSet algorithm | Standard AutoSet | Improved AutoSet + integrated AutoSet For Her |
| Humidifier | HumidAir II (standard water chamber) | HumidAir 11 Cleanable (washable design, fewer deposits) |
| Compatible heated tubing | ClimateLineAir (standard) | ClimateLineAir 11 (new generation) |
| myAir app | Standard myAir (score, basic data) | Enhanced myAir (Care Check-In, Personal Therapy Assistant, Test Drive) |
| OTA software updates | No | Yes (over-the-air) |
| Pressure range | 4 - 20 cmH₂O | 4 - 20 cmH₂O |
| EPR (Pressure Relief) | Yes (levels 1, 2, 3) | Yes (levels 1, 2, 3) |
| SmartStart / SmartStop | Yes | Yes |
| Pressure ramp | Yes | Yes |
| SD card | Yes (OSCAR-compatible data) | Yes (OSCAR-compatible data) |
| Airplane mode | Yes | Yes |
Key differences between the AirSense 10 and AirSense 11
1. Native cellular connectivity
This is the most significant difference for remote monitoring. The AirSense 11 has built-in cellular connectivity: treatment data is transmitted automatically without requiring a WiFi network. This facilitates monitoring by your doctor or sleep centre, even when travelling.
The AirSense 10, depending on the version, had a WiFi module - but data transmission depended on home network quality and required the device to be within range of the router.
2. AutoSet algorithm and AutoSet For Her
Both devices use ResMed's AutoSet algorithm. On the AirSense 11, the algorithm is an improved version that directly integrates AutoSet For Her mode - adapted to the female apnea profile (often more hypopnea-related, linked to REM sleep). On the AirSense 10, this mode existed only on the dedicated "For Her" device version.
3. Humidifier: HumidAir II vs HumidAir 11 Cleanable
The AirSense 11 comes with the HumidAir 11 Cleanable, an open, washable water chamber design - easier to clean and less prone to visible limescale deposits. The AirSense 10 used the HumidAir II, a more enclosed chamber, harder to clean thoroughly.
4. Heated tubing: ClimateLineAir vs ClimateLineAir 11
Both generations use different and non-interchangeable heated tubes:
- AirSense 10: ClimateLineAir
- AirSense 11: ClimateLineAir 11
5. myAir: enhanced experience on the AirSense 11
The myAir app works with both devices, but the AirSense 11 offers coaching features absent on the AirSense 10:
- Care Check-In: daily wellbeing questionnaire to monitor how you feel.
- Personal Therapy Assistant: personalised coaching based on your treatment data.
- Test Drive: familiarisation function with the device before the first full night.
To learn how to read your myAir results, see our guide on reading your myAir results.
Accessory compatibility
| Accessory | AirSense 10 | AirSense 11 | Interchangeable? |
|---|---|---|---|
| Standard tubing | Universal standard tubing | Universal standard tubing | Yes |
| Heated tubing | ClimateLineAir | ClimateLineAir 11 | No |
| Humidifier | HumidAir II | HumidAir 11 Cleanable | No |
| Masks (all brands) | Compatible (standard connection) | Compatible (standard connection) | Yes |
| Filters | AirSense 10-specific | AirSense 11-specific | No |
Which device is right for you?
The AirSense 10 is still relevant if…
- You want a simple, robust and reliable device at a reduced price (clearance stock).
- You already own AirSense 10 accessories (ClimateLineAir, HumidAir II) you wish to keep.
- You don't need cellular connectivity (WiFi monitoring is sufficient, or no remote monitoring required).
- Advanced myAir coaching is not a priority for you.
The AirSense 11 is recommended if…
- You want the most recent device with the best long-term support outlook.
- Native cellular connectivity matters to you - for easy remote monitoring without depending on WiFi.
- You want the HumidAir 11 Cleanable humidifier (fewer deposits, easier cleaning).
- You want access to advanced myAir features (Care Check-In, Personal Therapy Assistant).
- You are starting CPAP therapy and want new equipment with guaranteed software updates.
For more detail, see our complete AirSense 11 guide.
What about the AirSense 11 Elite?
The AirSense 11 Elite is the fixed-pressure version of the AirSense 11 (no AutoSet algorithm). Your doctor will tell you whether a fixed-pressure CPAP or an Auto-CPAP is right for your situation. In the absence of a specific indication, most new patients are equipped with an Auto-CPAP (AutoSet mode).
FAQ — AirSense 10 vs AirSense 11
It's mainly more modern: touchscreen, Bluetooth, coaching tools and software updates. In terms of pure therapy quality, both are very similar — they use the same AutoSet algorithm with the same pressure range. The best choice depends on your profile and how much value you place on digital support.
The AirSense 10 has been discontinued by ResMed. You may still find it as remaining stock from some retailers, but quantities are very limited and won't be restocked. The AirSense 11 is now the current model. Replacement parts for the AirSense 10 (filters, water chambers, hoses) remain available for existing users.
Partially. Masks, standard hoses and the swivel elbow are compatible with both. However, filters (different part numbers), HumidAir water chambers, ClimateLineAir heated hoses and power supplies are model-specific and not interchangeable.
No. Each model uses a uniquely shaped water chamber. The AirSense 10 chamber doesn't fit the 11, and vice versa.
The rated noise levels are virtually identical (≈ 26–27 dBA). The difference is imperceptible in practice. Perceived noise depends mainly on the mask, leaks, hose type and the environment around your bedside table.
No. On the AirSense 10, you need a separate model (AirSense 10 AutoSet For Her). On the AirSense 11, For Her mode is built into all AutoSet models and can be activated in the settings.
The AirSense 11 (65 W vs 90 W). In normal use the difference is minimal, but it matters if you're using a backup battery or power converter while travelling.
No. CPAP masks are compatible with both machines. However, you will need to change the filters (different part numbers), water chamber, heated hose and power supply.
Not necessarily. If your therapy is going well, you can continue without any issues — the therapy quality is the same. Replacement parts remain available. Upgrading mainly makes sense if you want Bluetooth, a more compact machine for travel, or if your current device is starting to show signs of wear.
Daily maintenance is the same for both models: empty and dry the water chamber and hose each morning. Once a week, hand-wash the mask, hose and water chamber with warm water and mild soap, then rinse and air dry. ResMed also recommends soaking the water chamber once a week for 15 to 20 minutes in a mixture of water and white vinegar (9:1) to dissolve limescale deposits. Avoid ozone- or UV-based cleaners.